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I think the best approach is to first take time to sketch ideas and formulate concepts. This allows you to plan and figure out what really needs to be done and think at a high level about implementation. Keeping it simple is your best friend. Think in resuable components to not only make the coding easier, but to make the design cohesive. Tools can speed up and make your pages more robust. But, as with anything in life, be sure to pick the right tool for the job. Don't make a simpler task more complex.